Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer.
Identifieur interne : 000070 ( Main/Exploration ); précédent : 000069; suivant : 000071Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer.
Auteurs : Michele Colicchia [États-Unis] ; Vidit Sharma [États-Unis] ; Firas Abdollah [États-Unis] ; Alberto Briganti [Italie] ; R. Jeffrey Karnes [États-Unis]Source :
- Current urology reports [ 1534-6285 ] ; 2017.
Abstract
Extent of pelvic lymph node dissection (PLND) during radical prostatectomy (RP) remains a subject of debate. Here, we review the literature covering the value of extended PLND (ePLND) during RP for high-risk prostate cancer (PCa) over a standard PLND, with a focus on potential therapeutic advantage. PLND may provide valuable prognostic information to high-risk PCa patients, and incorporating the common iliac and presacral nodes to ePLND templates further improves pathologic nodal staging accuracy. Although increased PLND extent is associated with increased lymphocele/lymphedema rates, it is not associated with increased venous thromboembolism rates. The therapeutic role of ePLND remains uncertain. While recent retrospective studies suggest an increased number of nodes removed within the ePLND template are associated with improved survival outcomes, such retrospective studies cannot completely adjust for the Will Rodgers phenomenon or surgeon-specific factors. Thus, the results of randomized trials are eagerly awaited in this arena.
DOI: 10.1007/s11934-017-0696-5
PubMed: 28589397
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000157
- to stream PubMed, to step Curation: 000157
- to stream PubMed, to step Checkpoint: 000157
- to stream Ncbi, to step Merge: 009170
- to stream Ncbi, to step Curation: 009170
- to stream Ncbi, to step Checkpoint: 009170
- to stream Main, to step Merge: 000070
- to stream Main, to step Curation: 000070
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer.</title><author><name sortKey="Colicchia, Michele" sort="Colicchia, Michele" uniqKey="Colicchia M" first="Michele" last="Colicchia">Michele Colicchia</name><affiliation wicri:level="2"><nlm:affiliation>Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, Mayo Clinic Rochester, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Sharma, Vidit" sort="Sharma, Vidit" uniqKey="Sharma V" first="Vidit" last="Sharma">Vidit Sharma</name><affiliation wicri:level="2"><nlm:affiliation>Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, Mayo Clinic Rochester, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Abdollah, Firas" sort="Abdollah, Firas" uniqKey="Abdollah F" first="Firas" last="Abdollah">Firas Abdollah</name><affiliation wicri:level="2"><nlm:affiliation>Center for Outcomes Research Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Outcomes Research Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Briganti, Alberto" sort="Briganti, Alberto" uniqKey="Briganti A" first="Alberto" last="Briganti">Alberto Briganti</name><affiliation wicri:level="3"><nlm:affiliation>Division of Oncology/Unit of Urology, Urological Research Institute, San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Oncology/Unit of Urology, Urological Research Institute, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Jeffrey Karnes, R" sort="Jeffrey Karnes, R" uniqKey="Jeffrey Karnes R" first="R" last="Jeffrey Karnes">R. Jeffrey Karnes</name><affiliation wicri:level="2"><nlm:affiliation>Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA. karnes.r@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, Mayo Clinic Rochester, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2017">2017</date><idno type="RBID">pubmed:28589397</idno><idno type="pmid">28589397</idno><idno type="doi">10.1007/s11934-017-0696-5</idno><idno type="wicri:Area/PubMed/Corpus">000157</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000157</idno><idno type="wicri:Area/PubMed/Curation">000157</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000157</idno><idno type="wicri:Area/PubMed/Checkpoint">000157</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000157</idno><idno type="wicri:Area/Ncbi/Merge">009170</idno><idno type="wicri:Area/Ncbi/Curation">009170</idno><idno type="wicri:Area/Ncbi/Checkpoint">009170</idno><idno type="wicri:Area/Main/Merge">000070</idno><idno type="wicri:Area/Main/Curation">000070</idno><idno type="wicri:Area/Main/Exploration">000070</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer.</title><author><name sortKey="Colicchia, Michele" sort="Colicchia, Michele" uniqKey="Colicchia M" first="Michele" last="Colicchia">Michele Colicchia</name><affiliation wicri:level="2"><nlm:affiliation>Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, Mayo Clinic Rochester, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Sharma, Vidit" sort="Sharma, Vidit" uniqKey="Sharma V" first="Vidit" last="Sharma">Vidit Sharma</name><affiliation wicri:level="2"><nlm:affiliation>Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, Mayo Clinic Rochester, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author><author><name sortKey="Abdollah, Firas" sort="Abdollah, Firas" uniqKey="Abdollah F" first="Firas" last="Abdollah">Firas Abdollah</name><affiliation wicri:level="2"><nlm:affiliation>Center for Outcomes Research Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Center for Outcomes Research Analytics and Evaluation, Vattikuti Urology Institute, Henry Ford Health System, Detroit, MI</wicri:regionArea><placeName><region type="state">Michigan</region></placeName></affiliation></author><author><name sortKey="Briganti, Alberto" sort="Briganti, Alberto" uniqKey="Briganti A" first="Alberto" last="Briganti">Alberto Briganti</name><affiliation wicri:level="3"><nlm:affiliation>Division of Oncology/Unit of Urology, Urological Research Institute, San Raffaele Scientific Institute, Milan, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Division of Oncology/Unit of Urology, Urological Research Institute, San Raffaele Scientific Institute, Milan</wicri:regionArea><placeName><settlement type="city">Milan</settlement><region nuts="2">Lombardie</region></placeName></affiliation></author><author><name sortKey="Jeffrey Karnes, R" sort="Jeffrey Karnes, R" uniqKey="Jeffrey Karnes R" first="R" last="Jeffrey Karnes">R. Jeffrey Karnes</name><affiliation wicri:level="2"><nlm:affiliation>Department of Urology, Mayo Clinic Rochester, Rochester, MN, USA. karnes.r@mayo.edu.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Urology, Mayo Clinic Rochester, Rochester, MN</wicri:regionArea><placeName><region type="state">Minnesota</region></placeName></affiliation></author></analytic><series><title level="j">Current urology reports</title><idno type="eISSN">1534-6285</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Extent of pelvic lymph node dissection (PLND) during radical prostatectomy (RP) remains a subject of debate. Here, we review the literature covering the value of extended PLND (ePLND) during RP for high-risk prostate cancer (PCa) over a standard PLND, with a focus on potential therapeutic advantage. PLND may provide valuable prognostic information to high-risk PCa patients, and incorporating the common iliac and presacral nodes to ePLND templates further improves pathologic nodal staging accuracy. Although increased PLND extent is associated with increased lymphocele/lymphedema rates, it is not associated with increased venous thromboembolism rates. The therapeutic role of ePLND remains uncertain. While recent retrospective studies suggest an increased number of nodes removed within the ePLND template are associated with improved survival outcomes, such retrospective studies cannot completely adjust for the Will Rodgers phenomenon or surgeon-specific factors. Thus, the results of randomized trials are eagerly awaited in this arena.</div></front></TEI><affiliations><list><country><li>Italie</li><li>États-Unis</li></country><region><li>Lombardie</li><li>Michigan</li><li>Minnesota</li></region><settlement><li>Milan</li></settlement></list><tree><country name="États-Unis"><region name="Minnesota"><name sortKey="Colicchia, Michele" sort="Colicchia, Michele" uniqKey="Colicchia M" first="Michele" last="Colicchia">Michele Colicchia</name></region><name sortKey="Abdollah, Firas" sort="Abdollah, Firas" uniqKey="Abdollah F" first="Firas" last="Abdollah">Firas Abdollah</name><name sortKey="Jeffrey Karnes, R" sort="Jeffrey Karnes, R" uniqKey="Jeffrey Karnes R" first="R" last="Jeffrey Karnes">R. Jeffrey Karnes</name><name sortKey="Sharma, Vidit" sort="Sharma, Vidit" uniqKey="Sharma V" first="Vidit" last="Sharma">Vidit Sharma</name></country><country name="Italie"><region name="Lombardie"><name sortKey="Briganti, Alberto" sort="Briganti, Alberto" uniqKey="Briganti A" first="Alberto" last="Briganti">Alberto Briganti</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/LymphedemaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000070 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000070 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= LymphedemaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:28589397
|texte= Therapeutic Value of Standard Versus Extended Pelvic Lymph Node Dissection During Radical Prostatectomy for High-Risk Prostate Cancer.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:28589397" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a LymphedemaV1
| This area was generated with Dilib version V0.6.31. |  |